产品货号：
Z17344
中文名称：
GPR124/ADGRA2抗体
英文名称：
Anti-GPR124/ADGRA2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GPR124/ADGRA2 Antibody |
| 指标别名 | Adhesion G protein-coupled receptor A2;G-protein coupled receptor 124;Tumor endothelial marker 5;ADGRA2;GPR124;KIAA1531;TEM5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | ADGRA2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TEM5 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM5.The immunogen is located within amino acids 1270 - 1320 of TEM5. |
| 计算分子量 | 143kDa |
| 成分 | TEM5 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TEM5 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors.TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.These include TEMs such as TEM1,TEM5,TEM7 and TEM8.TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells.TEM5 is a seven-pass transmembrane receptor,unlike TEM1,TEM7 and TEM8 which span the membrane once.TEM5 is abundantly expressed in tumor vessels,heart,placenta,ovary,small intestine,and colon.Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans. |
| Uniprot ID | Q96PE1 |
| 基因名全称 | G protein-coupled receptor 124 |
| 蛋白名全称 | G protein-coupled receptor 124 |
| 推荐稀释比 | TEM5 antibody can be used for detection of TEM5 by Western blot at 2 and 4μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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